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Case Studies :


  • Mercury Therapeutics

    Taking AMPK target knowledge (no crystal structure), implementing four FTE medicinal chemistry programs and generating an orally bioavailable developmental candidate through scaffold morphing, lead generation and lead optimization iterations in nine months. Participated in due diligence by potential investors. IP was generated.

  • MaxThera

    Taking a 10 micromolar anti-infective lead compound to a sub-nanomolar advanced lead candidate in six months. IP was generated.

  • Augusta Therapeutics

    Designing 100-membered optimized libraries and delivering two micromlar lead compounds.

 
News
  CreaGen Inc. makes into the 2018 list of major players in CRO industry
https://www.businesswire.com/news/home/20180412005808/en/Outsourcing-Drug-Discovery-Contract-Research-Organization-CRO https://themobileherald.com/contract-research-organization-market-industry-growth-and-forecast-analysis-report-till-2024/24870/ https://www.businesswire.com/news/home/20180412005808/en/Outsourcing-Drug-Discovery-Contract-Research-Organization-CRO   more...
    7th Advances In Chemical Sciences Symposium: May 4th, 2018
The Seventh Annual Advances in Chemical Sciences Symposium Royal Sonesta Hotel Cambridge, MA: May 4th, 2018 A day-long symposium focused on Medicinal Chemistry, Organic Synthesis, and Methodology, featuring eminent scientists from industry and academia. Speakers: Professor Richard R. Schrock (MIT): “TBA” Professor Dale L. Boger (Scripps Research Institute): “Redesign of Vancomycin for Resistant Bacteria” Professor Laura Kiessling (MIT): “TBA” Dr. Sue Ashwell (Forma Therapeutics): “Discovery and Optimization of a Novel Series of Inhibitors of mt-IDH1” Dr. Michael Hoemann (Abbvie): “Discovery and Optimization of Spleen Tyrosine Kinase Inhibitors for Immunological Diseases” Dr. Frank Salituro (Sage Therapeutics): “Discovery and Clinical Development of SAGE-217: A Next Generation Neuroactive Steroid Positive Allosteric Modulator of the (GABA)A Receptor” Plus: Vendor Exhibition Hall and Networking Reception   more...
 
 
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